UNDEPRE (DESYREL) INDICATIONS
Undepre is used for treating depression. It may also be used for relief of an anxiety disorder (eg, sleeplessness, tension), chronic pain. Undepre is an antidepressant. It is thought to increase the activity of one of the brain chemicals (serotonin), which helps elevate mood.
UNDEPRE (DESYREL) INSTRUCTIONS
Use Undepre as directed by your doctor.
- Take Undepre shortly after a meal or light snack.
- It may take 1 to 4 weeks for Undepre to work. Do not stop taking Undepre without checking with your doctor.
- If a dose is missed, take it as soon as possible. If several hours have passed or if it is nearing time for the next dose, do not double the dose to catch up. If more than one dose is missed, restart medication and advise your doctor or pharmacist at your next appointment.
Ask your health care provider any questions you may have about how to use Undepre.
UNDEPRE (DESYREL) STORAGE
Store Undepre at room temperature, between 68 and 77 degrees F (20 and 25 degrees C) in a tight, light-resistant container. Store away from heat, moisture, and light. Protect from temperatures above 104 degrees F (40 degrees C). Do not store in the bathroom. Keep Undepre out of the reach of children and away from pets.
UNDEPRE (DESYREL) MORE INFO:
Active Ingredient:
Do NOT use Undepre if:
- you are allergic to any ingredient in Undepre or nefazodone
- you are taking sodium oxybate (GHB).
Contact your doctor or health care provider right away if any of these apply to you.
Some medical conditions may interact with Undepre. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
- if you are pregnant, planning to become pregnant, or are breast-feeding
- if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
- if you have allergies to medicines, foods, or other substances
- if you have heart disease including irregular heartbeat or have had a heart attack
- if you have a history of depression or suicidal tendencies
- if you are scheduled to have surgery
- if you consume alcoholic beverages.
Some medicines may interact with Undepre. Tell your health care provider if you are taking any other medicines, especially any of the following:
- Carbamazepine, ethanol, ginkgo biloba, HIV protease inhibitors (eg, ritonavir), phenothiazines (eg, thioridazine), or serotonin reuptake inhibitors (eg, fluoxetine) because side effects, such as increased drowsiness or blurred vision, may occur
- Buspirone, carbamazepine, digoxin, hydantoins (eg, phenytoin), itraconazole, ketoconazole, nefazodone, serotonin reuptake inhibitors (eg, fluoxetine), or sodium oxybate (GHB) because the risk of their side effects may be increased by Undepre
- Anticoagulants (eg, warfarin) because they may decrease Undepre's effectiveness. Your doctor may want to adjust your dose while taking Undepre.
This may not be a complete list of all interactions that may occur. Ask your health care provider if Undepre may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.
Important safety information:
- Undepre may cause drowsiness, dizziness, or blurred vision. These effects may be worse if you take it with alcohol or certain medicines. Use Undepre with caution. Do not drive or perform other possible unsafe tasks until you know how you react to it.
- Do not drink alcohol or use medicines that may cause drowsiness (eg, sleep aids, muscle relaxers) while you are using Undepre; it may add to their effects. Ask your pharmacist if you have questions about which medicines may cause drowsiness.
- Tell your doctor or dentist that you take Undepre before you receive any medical or dental care, emergency care, or surgery.
- Undepre should not be used in children younger 6 years; safety and effectiveness in these children have not been confirmed.
- Undepre may rarely cause a prolonged, painful erection. This could happen even when you are not having sex. If this is not treated right away, it could lead to permanent sexual problems, such as impotence. Contact your doctor right away if this happens.
- Pregnancy and breast-feeding: If you think you may be pregnant, contact your doctor. You will need to discuss the benefits and risks of using Undepre while you are pregnant. Undepre is found in breast milk. If you are or will be breast-feeding while you use Undepre, check with your doctor. Discuss any possible risks to your baby.
All medicines may cause side effects, but many people have no, or minor, side effects.
Check with your doctor if any of these most common side effects persist or become bothersome:
Blurred vision; constipation; decreased appetite; dizziness; drowsiness; dry mouth; general body discomfort; headache; incoordination; light-headedness; muscle aches/pains; nausea; nervousness; sleeplessness; stomach pain; stuffy nose; swelling of the skin; tiredness; tremors.
Seek medical attention right away if any of these severe side effects occur:
Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); blood in urine; chest pain; fainting; hallucinations; irregular heartbeat; light-headedness when rising from a lying or seated position; prolonged, inappropriate, or painful erections; seizures; shortness of breath; stroke; vomiting.
This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider.