Data shows potential health benefits of S-equol in relieving menopausal symptoms

March 31, 2016

The change in estrogen levels during menopause can also affect bone health.  Clinical evidence demonstrates that S-equol can help preserve bone.  In one study, women who could produce S-equol had a significantly lower percent change in bone loss at the total hip (a decrease of 0.46 percent) than that of the nonproducers (a decrease of 2.28 percent). Furthermore, a two-year randomized placebo-controlled trial that characterized postmenopausal women by their S-equol-producing status, showed that those who were S-equol producers had a 2.4 percent increase in the lumbar spine bone mineral density (BMD) compared with just 0.6 percent increase in the S-equol non-producers. These results suggest that using soy isoflavones to prevent bone loss in women in early post-menopause may depend on an individual's S-equol-producing capacity.

SOURCE Journal of Nutrition