African ancestry associated with triple-negative breast cancer: Study
April 07, 2016
Prior studies have shown that while African-American women are less likely than white women to develop breast cancer, those who are diagnosed are usually younger and are more likely to die from the disease. These characteristics, including the triple negative disease, are also more common among women with a known hereditary predisposition for breast cancer related to BRCA1 gene mutations. Other studies have also shown a hereditary breast cancer risk associated with racial-ethnic identity -- most commonly among Ashkenazi Jewish women.
"African ancestry might be associated with other links to hereditary predisposition for particular patterns of breast cancer. We hope that by studying breast cancer in African and African-American women we can identify biomarkers that might be useful for assessing risk or treating triple-negative breast cancer," says Newman, professor of surgery at the U-M Medical School.
Breast cancer statistics: 194,280 Americans will be diagnosed with breast cancer this year and 40,610 will die from the disease, according to the American Cancer Society
Source : American Cancer Society