INAPAS (ISONIAZID) INDICATIONS
Inapas is used for treating or preventing tuberculosis (TB). If you are using Inapas to treat TB, it should always be used along with another medicine. Inapas is an antibacterial. It works by killing TB organisms.soniazid also has an antidepressant effect, and it was one of the first antidepressants discovered. Inapas can also be used in the treatment of a BCG-oma.
INAPAS (ISONIAZID) INSTRUCTIONS
Use Inapas as directed by your doctor.
- Take each dose with a full glass (8 ounces) of water.
- Take Inapas on an empty stomach 1 hour before or 2 hours after meals. If nausea occurs, ask your doctor if you can take Inapas with food.
- Take all of the Inapas that has been prescribed for you even if you begin to feel better. Your symptoms may begin to improve before the infection is completely treated.
- It is important to take Inapas regularly to get the most benefit.
- Your doctor may also want you to take a supplemental vitamin B6 (pyridoxine) tablet daily during treatment to prevent numbness and tingling caused by low levels of this vitamin.
- Your doctor may want you to have blood tests or other medical evaluations during treatment with isoniazid to monitor progress and side effects.
- Continue to use Inapas even if you feel well. Do not miss any dose.
- If you miss a dose of Inapas, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.
Ask your health care provider any questions you may have about how to use Inapas.
INAPAS (ISONIAZID) STORAGE
Store Inapas between 68 and 77 degrees F (20 and 25 degrees C). Brief storage at temperatures between 59 and 86 degrees F (15 and 30 degrees C) is permitted. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Inapas out of the reach of children and away from pets.
Do NOT use Inapas if:
- you are allergic to any ingredient in Inapas or have had severe side effects from isoniazid, such as drug fever, chills, or arthritis
- you have severe liver damage, active liver disease, or liver damage from previous use of Inapas
- you have a history of hepatitis caused by any medicine.
Contact your doctor or health care provider right away if any of these apply to you.
Some medical conditions may interact with Inapas. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
- if you are pregnant, planning to become pregnant, or are breast-feeding
- if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
- if you have allergies to medicines, foods, or other substances
- if you have diabetes, kidney problems, nerve problems (eg, neuropathy) or risk of nerve problems, HIV, or a history of liver problems
- if you have a history of alcohol or other substance abuse, have unsanitary injectable drug habits, or drink alcohol daily
- if you are older than 35 years old, you have recently given birth, or you have previously taken Inapas.
Some medicines may interact with Inapas. Tell your health care provider if you are taking any other medicines, especially any of the following:
- Acetaminophen, anticoagulants (eg, warfarin), carbamazepine, hydantoins (eg, phenytoin), rifampin, theophylline, or valproic acid because the risk of their side effects may be increased by Inapas
- Ketoconazole because its effectiveness may be decreased by Inapas.
This may not be a complete list of all interactions that may occur. Ask your health care provider if Inapas may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.
Important safety information:
- Check with your doctor before drinking alcohol while using Inapas. Alcohol may increase the risk of liver problems. If you have a history of alcohol abuse, you may also be at increased risk of developing nerve problems from Inapas. Notify your doctor if you notice any unusual tingling or numbness in your hands or feet.
- If you have a history of diabetes, alcohol abuse, or poor nutrition, your doctor may recommend that you also take vitamin B6
- Do not eat foods high in tyramine while you use Inapas. Eating foods high in tyramine (eg, aged cheeses, red wines, beer, certain meats and sausages, liver, sour cream, soy sauce, raisins, bananas, avocados) while you use Inapas may cause severe high blood pressure. Seek medical attention at once if symptoms of severe high blood pressure occur. These may include severe headache, fast or irregular heartbeat, sore or stiff neck, nausea, vomiting, sweating, enlarged pupils, or sensitivity to light.
- Do not eat foods high in histamine while you use Inapas. Eating foods high in histamine (eg, skipjack, tuna, tropical fish) while you use Inapas may cause low blood pressure, irregular heartbeat, headache, sweating, or flushing. Contact your doctor at once if any of these symptoms occur.
- Ask your health care provider for a complete list of all foods you should avoid while you are using Inapas.
- Inapas only works against TB bacteria; it does not treat viral infections (eg, the common cold).
- Be sure to use Inapas for the full course of treatment. If you do not, the medicine may not clear up your infection completely. The bacteria could also become less sensitive to this or other medicines. This could make the infection harder to treat in the future.
- Diabetes patients - Inapas may affect your blood sugar. Check blood sugar levels closely. Ask your doctor before you change the dose of your diabetes medicine. You may also be at increased risk of developing nerve problems from Inapas. Contact your doctor if you notice any unusual tingling in your hands or feet.
- Lab tests, including liver function and eye exams, may be performed while you use Inapas. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
- Use Inapas with caution in black and Hispanic women; they may have a greater risk of severe liver problems from Inapas.
- Use Inapas with caution in patients older 35 years; they may have a greater risk of severe liver problems from Inapas.
- Pregnancy and breast-feeding: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Inapas while you are pregnant. Inapas is found in breast milk. If you are or will be breast-feeding while you use Inapas, check with your doctor. Discuss any possible risks to your baby.
All medicines may cause side effects, but many people have no, or minor, side effects.
Check with your doctor if any of these most common side effects persist or become bothersome:
Mild stomach upset.
Seek medical attention right away if any of these severe side effects occur:
Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); changes in vision; chills or fever; dark urine; general feeling of discomfort; increased thirst or urination; joint pain or swelling; loss of appetite; memory problems; mental or mood changes; nausea; seizures; stomach pain or tenderness; symptoms of low vitamin B6 This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider.