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ISMO (IMDUR) INDICATIONS

Ismo (isosorbide mononitrate) is in a group of drugs called nitrates. It dilates (widens) blood vessels, making it easier for blood to flow through them and easier for the heart to pump.

ISMO (IMDUR) INSTRUCTIONS

Take Ismo exactly as prescribed by your doctor.

Take this medication with at least 4 ounces of water or other liquid. Do not crush, chew, or break an extended-release tablet. Swallow the pill whole.

If possible, try to rest or stay seated when you use this medication. Ismo can cause dizziness or fainting. Use Ismo regularly to prevent an angina attack.

Do not stop taking Ismo suddenly. Stopping suddenly could cause a severe angina attack.

ISMO (IMDUR) STORAGE

The usual adult dose of Ismo is 30-60 mg orally once a day. Follow your doctor's dosing instructions very carefully.

ISMO (IMDUR) STORAGE

Store this medicine at room temperature away from moisture, heat, and light. Keep the bottle tightly closed when not in use.

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To make sure you can safely take Ismo, tell your doctor if you have any of these other conditions:

congestive heart failure;
low blood pressure; or
kidney disease.

Tell your doctor about all other medications you use, especially:

blood pressure medication;
dihydroergotamine (D.H.E. 45, Migranal) or ergotamine (Ergomar, Cafergot, and others);
an erectile dysfunction medication such as tadalafil (Cialis) or vardenafil (Levitra);
a beta blocker such as atenolol (Tenormin, Tenoretic), carvedilol (Coreg), labetalol (Normodyne, Trandate), metoprolol (Dutoprol, Lopressor, Toprol), nadolol (Corgard), propranolol (Inderal, InnoPran), sotalol (Betapace), and others;
heart or blood pressure medicine such as amlodipine (Norvasc, Caduet, Exforge, Lotrel, Tekamlo, Tribenzor, Twynsta, Amturnide), diltiazem (Cartia, Cardizem), nifedipine (Nifedical, Procardia), verapamil (Calan, Covera, Isoptin, Verelan), and others.

It is not known whether Ismo will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication. It is not known whether isosorbide mononitrate passes into breast milk or if it could harm a nursing baby. Do not use Ismo without telling your doctor if you are breast-feeding a baby.

Call your doctor at once if you have a serious side effect such as:

fast, slow, pounding, or uneven heart rate;
feeling like you might pass out;
trouble breathing, blue-colored skin, tired feeling; or
worsening angina pain.

Less serious Ismo side effects may include:

headache, mild dizziness;
warmth, redness, or tingling under your skin;
nausea, vomiting, constipation, diarrhea;
pain or stiffness in joints or muscles;
hot flashes; or
dry mouth.



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