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DUFINE (CLOMID) INDICATIONS

Dufine is used for treating female infertility and for certain conditions as determined by your doctor. Dufine is an ovulatory stimulant. It works by helping to produce more hormones that cause your ovaries to release.

DUFINE (CLOMID) INSTRUCTIONS

Use Dufine as directed by your doctor.

  • Take Dufine by mouth with or without food.
  • Properly timed sexual intercourse is important for good results. Ovulation usually occurs 5 to 10 days after a dose of Dufine.
  • If pregnancy has not been successful after 3 courses of treatment, further treatment is not recommended. Long-term use of Dufine is not recommended.
  • If you miss a dose of Dufine, contact your doctor right away.

Ask your health care provider any questions you may have about how to use Dufine.

DUFINE (CLOMID) STORAGE

Store Dufine at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Dufine out of the reach of children and away from pets.
DUFINE (CLOMID) MORE INFO:

Active Ingredient:Clomiphene.

Do NOT use Dufine if:

  • you are allergic to any ingredient in Dufine
  • you are pregnant
  • you have abnormal vaginal bleeding
  • you have ovarian cysts (small growths on the ovaries) or enlargement not due to polycystic ovarian syndrome
  • you have or have ever had blockage of blood vessels (blood clots) in the legs, lungs, or other parts of the body
  • you have liver problems, uncontrolled thyroid or adrenal gland problems, or a brain lesion (eg, pituitary gland tumor).

Contact your doctor or health care provider right away if any of these apply to you.

Some medical conditions may interact with Dufine. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are planning to become pregnant or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have depression, endometriosis, polycystic ovarian syndrome, or uterine fibroids.

Some medicines may interact with Dufine. However, no specific interactions with Dufine are known at this time. Ask your health care provider if Dufine may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

Important safety information:

  • Dufine may cause dizziness, lightheadedness, or vision disturbances, including blurring, spots, and flashes. These effects may be worse if you take it with alcohol or certain medicines. Use Dufine with caution. Do not drive or perform other possible unsafe tasks until you know how you react to it.
  • Enlargement of the ovaries may happen during or shortly after taking Dufine. Call your health care provider if you experience any stomach or pelvic pain, weight gain, pain, or stomach enlargement or discomfort while taking Dufine.
  • Pregnancy with more than 1 fetus (eg, twins) is possible while you are taking Dufine. Be sure you have discussed the potential complications and hazards of multiple pregnancy.
  • Lab tests, including pregnancy tests, may be performed while you use Dufine. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
  • Use Dufine with caution in the elderly; they may be more sensitive to its effects.
  • Dufine should not be used in children; safety and effectiveness in children have not been confirmed.
  • Pregnancy and breast-feeding: Do not use Dufine if you are pregnant. Avoid becoming pregnant while you are taking it. If you think you may be pregnant, contact your doctor right away. It is not known if Dufine is found in breast milk. Do not breastfeed while taking Dufine.

All medicines may cause side effects, but many people have no, or minor, side effects.

Check with your doctor if any of these most common side effects persist or become bothersome:

Blurred vision or vision problems (spots or flashes); breast tenderness; dizziness; enlarged breasts; enlargement of the ovaries; flushing; headache; hot flashes; lightheadedness; mood change; nausea; pelvic pain or bloating; stomach pain; vomiting.

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue)increased risk of cancer of the ovaries; over stimulation of the ovaries; spontaneous abortion.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider.



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