DEPREVEX (MICARDIS) INDICATIONS
Deprevex is used for treating high blood pressure alone or with other medicines. It is also used to reduce the risk of heart attack, stroke, or death due to heart problems in certain patients. Deprevex is an angiotensin II receptor blocker (ARB). It works by relaxing blood vessels, which helps to lower blood pressure.
DEPREVEX (MICARDIS) INSTRUCTIONS
Use Deprevex as directed by your doctor.
- Take Deprevex by mouth with or without food.
- Do not remove the tablet from the blister seal until you are ready to take your dose.
- Take Deprevex on a regular schedule to get the most benefit from it. Taking Deprevex at the same time each day will help you remember to take it.
- Continue to take Deprevex even if you feel well. Do not miss any dose.
- If you miss a dose of Deprevex, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.
Ask your health care provider any questions you may have about how to use Deprevex.
DEPREVEX (MICARDIS) STORAGE
Store Deprevex at 77 degrees F (25 degrees C). Brief storage at temperatures between 59 and 86 degrees F (15 and 30 degrees C) is permitted. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Deprevex out of the reach of children and away from pets.
DEPREVEX (MICARDIS) MORE INFO:
Do NOT use Deprevex if:
- you are allergic to any ingredient in Deprevex
- you are in your second or third trimester of pregnancy.
Contact your doctor or health care provider right away if any of these apply to you.
Some medical conditions may interact with Deprevex. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
- if you are pregnant, planning to become pregnant, or are breast-feeding
- if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
- if you have allergies to medicines, foods, or other substances
- if you are able to become pregnant
- if you have a history of angioedema (eg, swelling of the hands, face, lips, eyes, throat, or tongue; difficulty swallowing or breathing; hoarseness), including angioedema caused by treatment with an angiotensin-converting enzyme (ACE) inhibitor (eg, lisinopril)
- if you have a history of heart problems (eg, heart failure), blood vessel problems, blood flow problems, liver or kidney problems, gallbladder problems, or diabetes
- if you have a history of stroke or recent heart attack
- if you are dehydrated or have low blood volume
- if you have electrolyte problems (eg, high blood potassium levels, low blood sodium levels) or are on a low-salt (sodium) diet
- if you are on dialysis or are scheduled to have major surgery
- if you take another medicine for blood pressure or heart problems.
Some medicines may interact with Deprevex. Tell your health care provider if you are taking any other medicines, especially any of the following:
- Diuretics (eg, furosemide, hydrochlorothiazide) because the risk of low blood pressure may be increased
- Potassium-sparing diuretics (eg, spironolactone, triamterene) or potassium supplements because the risk of high blood potassium levels may be increased
- ACE inhibitors (eg, lisinopril, ramipril) because the risk of kidney problems may be increased
- Nonsteroidal anti-inflammatory drugs (NSAIDs) (eg, celecoxib, indomethacin) because they may decrease Deprevex's effectiveness
- Digoxin or lithium because the risk of their side effects may be increased by Deprevex.
This may not be a complete list of all interactions that may occur. Ask your health care provider if Deprevex may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.
Important safety information:
- Deprevex may cause dizziness, lightheadedness, or fainting. These effects may be worse if you take it with alcohol or certain medicines. Use Deprevex with caution. Do not drive or perform other possible unsafe tasks until you know how you react to it.
- Deprevex may cause dizziness, lightheadedness, or fainting; alcohol, hot weather, exercise, or fever may increase these effects. To prevent them, sit up or stand slowly, especially in the morning. Sit or lie down at the first sign of any of these effects.
- Deprevex may cause a serious side effect called angioedema. Contact your doctor at once if you develop swelling of the hands, face, lips, eyes, throat, or tongue; difficulty swallowing or breathing; or hoarseness.
- Deprevex may not work as well in black patients. Discuss any questions or concerns with your doctor.
- Dehydration, excessive sweating, vomiting, or diarrhea may increase the risk of low blood pressure. Contact your health care provider at once if any of these occur.
- Check with your doctor before you use a salt substitute or a product that has potassium in it.
- Tell your doctor or dentist that you take Deprevex before you receive any medical or dental care, emergency care, or surgery.
- Patients who take medicine for high blood pressure often feel tired or run down for a few weeks after starting treatment. Be sure to take your medicine even if you may not feel "normal." Tell your doctor if you develop any new symptoms.
- If you have high blood pressure, do not use nonprescription products that contain stimulants. These products may include diet pills or cold medicines. Contact your doctor if you have any questions or concerns.
- Lab tests, including blood pressure, blood electrolyte levels, and heart, kidney, or liver function, may be performed while you use Deprevex. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
- Deprevex should be used with extreme caution in children; safety and effectiveness in children have not been confirmed.
- Pregnancy and breast-feeding: Deprevex may cause birth defects or fetal death if you take it while you are pregnant. If you think you may be pregnant, contact your doctor right away. It is not known if Deprevex is found in breast milk. Do not breastfeed while taking Deprevex.
All medicines may cause side effects, but many people have no, or minor, side effects.
Check with your doctor if any of these most common side effects persist or become bothersome:
Back pain; diarrhea; dizziness; sinus pain or congestion; sore throat; upper respiratory tract infection.
Seek medical attention right away if any of these severe side effects occur:
Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue; unusual hoarseness); change in the amount of urine produced or painful urination; chest pain; difficulty swallowing; fast, slow, or irregular heartbeat; fever, chills, or persistent sore throat; increased or excessive sweating; muscle pain or cramps; severe or persistent vomiting or diarrhea; severe or persistent weakness; shortness of breath; swelling of the arms or legs; symptoms of low blood pressure (eg, fainting, lightheadedness, severe dizziness); tendon or joint pain.
This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider.